Leishmania IGG/IGM Test

Cat.No.: LEISH 493

INTENDED USE:

The Leishmania IgG/IgM Rapid Test is a lateral flow immunoassay for the simultaneous detection and differentiation of IgG and IgM to the subspecies of the Leishmania donovani (L. donovani), the Visceral leishmaniasis causative protozoans, in human serum or plasma. It is intended to be used as a screening test and as an aid in the diagnosis of the disease of Visceral leishmaniasis. Any reactive specimen with theLeishmania IgG/IgM Rapid Test must be confirmed with alternative testing method(s).

SUMMARY AND EXPLANATION:

Visceral leishmaniasis, or Kala-azar, is a disseminated infection caused by several subspecies of the L. donovani. The disease is estimated by the World Health Organization (WHO) to affect approximately 12 million people in 88 countries. It is transmitted to humans by bites of the Phlebotomus sandflies, which acquire infection from feeding on infected animals. Though it is a disease found in poor countries, in Southern Europe, it has become the leading opportunistic infection in AIDS patients.
Identification of L. donovani organism from the blood, bone marrow, liver, lymph nodes or the spleen provides a definite mean of diagnosis. Serological detection of anti-L. donovani IgM is found to be an excellent marker for the acute Visceral leishmaniasis. Tests used in clinic are included ELISA, fluorescent antibody or direct agglutination tests. Recently, utilization of L. donovani specific protein in the test has improved the sensitivity and specificity dramatically.
TheLeishmania IgG/IgM Rapid Test is a recombinant protein based serological test, which detects IgG and IgM antibodies to the L. Donovani simultaneously. The test provides a reliable result within 10 minutes without any instruments.

Product Details

Test Procedure & Result Interpretation:

Ordering Reference Information:
Cat.No
Description of Products
Format
Packing Size
Specimen
LEISH 493
Leishmania IGG/IGM Test
Cassette25TSerum/Plasma