Trypanosome Cruzi (Chagas) AB Test

Cat.No.: CHAG 492

INTENDED USE:

The Chagas Ab Combo Rapid Test is a lateral flow chromatographic immunoassay for the qualitative detection of IgG anti-Trypanosoma cruzi (T. cruzi) in human serum, plasma or whole blood. It is intended to be used as a screening test and as an aid in the diagnosis of infection with T. cruzi. Any reactive specimen with the Chagas Ab Combo Rapid Test must be confirmed with alternative testing method(s) and clinical findings.

SUMMARY AND EXPLANATION:

Chagas disease is an insect-borne, zoonotic infection by the protozoan T. cruzi, which causes a systemic infection of humans with acute manifestations and long term sequelae. It is estimated that 16-18 million individuals are infected worldwide, and roughly 50,000 people die each year from chronic Chagas disease (World Health Organization).
Buffy coat examination and xenodiagnosis used to be the most commonly methods in the diagnosis of acute T. cruzi infection. However, both methods are either time consuming or lack of sensitivity. Recently, serological test becomes the mainstay in the diagnosis of Chagas’s disease. In particularly, recombinant antigen based tests eliminate false-positive reactions which are commonly seen in the native antigen tests.
The Chagas Ab Combo Rapid Test is an instant antibody test which detects IgG antibodies the T. cruzi within 15 minutes without any instrument requirements. By utilizing T. cruzi specific recombinant antigen, the test is highly sensitive and specific.

Product Details

Test Procedure & Result Interpretation:

Ordering Reference Information:
Cat.No
Description of Products
Format
Packing Size
Specimen
CHAG 492
Trypanosome Cruzi (Chagas) AB Test
Cassette25TSerum/Plasma